AI-powered foodome characterization

The current knowledge is largely confined to a narrow set of approximately 150 food components catalogued by traditional databases. These components represent only a very small fraction of the total chemical complexity present in foods, while thousands (>100,000) of compounds and contaminants remain largely unquantified and underexplored. Understanding this “nutrient dark matter” would require identifying, cataloguing and quantifying the full spectrum of substances present in our food and present in accessible, AI-ready databases. The need for such information is today a bottleneck to make the nutrition field predictive and data driven, and has the potential to make food processing more efficient in bringing new foods items on the market. Efforts to create such datasets are underway but owing to the quantity of samples (hundreds of thousands of compounds across thousands of foods), such databases often rely on high-throughput experimental methods which do not allow a precise characterisation of the molecules identified. Proposals should address the following activities: develop and test validated AI algorithms capable of interpreting and annotating high-throughput foodomics data, for instance from untargeted mass-spectrometry or nuclear magnetic resonance; the AI algorithms should be capable to predict or infer the presence and concentration of compounds based on (incomplete) foodomics data via innovative approaches, for instance by considering phylogenic relationships between species. Moreover, this should help identify analytical methods and potential food safety hazards based on their similarity to known compounds; develop a European research and innovation network between Member States and Associated Countries in food exposome research to support the development, standardization, valorisation and dissemination of the AI results and considering existing initiatives such as the Centre for Excellence in the Periodic Table of Food Initiative from Wageningen University. The multi-actor approach is encouraged. Proposals should include industry in the consortia and academia, startups, SMEs and international initiatives. Collaboration with international partners is encouraged as well as with existing private companies in the EU/Associated countries. Technology Readiness Level - Technology readiness level expected from completed projects Activities are expected to start from TRL 5 in order to achieve TRL 7 by the end of the project – see General Annex B.

Eligibility and submission conditions

"> General conditions 1. Admissibility Conditions: Proposal page limit and layout described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes. Proposal page limits and layout: described in Part B of the Application Form available in the Submission System. 2. Eligible Countries described in Annex B of the Work Programme General Annexes. A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide . 3. Other Eligible Conditions In line with the “ restriction on control in innovation actions in critical technology areas ” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action. described in Annex B of the Work Programme General Annexes. 4. Financial and operational capacity and exclusion described in Annex C of the Work Programme General Annexes. 5a. Evaluation and award: Award criteria, scoring and thresholds are described in Annex D of the Work Programme General Annexes. 5b. Evaluation and award: Submission and evaluation processes are described in Annex F of the Work Programme General Annexes and the Online Manual . 5c. Evaluation and award: Indicative timeline for evaluation and grant agreement described in Annex F of the Work Programme General Annexes. 6. Legal and financial set-up of the grants The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5. described in Annex G of the Work Programme General Annexes. Specific conditions described in the [specific topic of the Work Programme] Application and evaluation forms and model grant agreement (MGA): Application form templates — the application form specific to this call is available in the Submission System Standard application form (HE RIA, IA) Evaluation form templates — will be used with the necessary adaptations Standard evaluation form (HE RIA, IA)   Guidance HE Programme Guide   Model Grant Agreements (MGA) HE MGA   Additional documents: HE Main Work Programme 2026-2027 – 1. General Introduction HE Main Work Programme 2026-2027 – 9. Food, Bioeconomy, Natural Resources, Agriculture and Environment HE Main Work Programme 2026-2027 – 15. General Annexes HE Programme Guide HE Framework Programme 2021/695 HE Specific Programme Decision 2021/764 EU Financial Regulation 2024/2509 Rules for Legal Entity Validation, LEAR Appointment and Financial Capacity Assessment EU Grants AGA — Annotated Model Grant Agreement Funding & Tenders Portal Online Manual   Funding & Tenders Portal Terms and Conditions   Funding & Tenders Portal Privacy Statement

Programme context

This destination will support the EU Commission priority ‘Sustaining our quality of life: food security, water and nature’. R&I will provide new knowledge and innovation in support of the EU Vision for Agriculture and Food, built on the recommendations of the Strategic Dialogue on Agriculture, to ensure the long-term competitiveness and sustainability of our farming, fisheries, aquaculture and food sector within the boundaries of our planet. The implementation of the Green Deal actions will continue to guide R&I in this destination to foster sustainable food systems, addressing potential trade-offs between economic competitiveness and environmental sustainability. The R&I activities under this Destination will contribute to the ambitious objectives of the current CAP concerning the competitiveness and sustainability of feed, food and non-food production as well as additional future CAP policy priorities. More specifically, actions will contribute to the specific objectives of the CAP; EU action plan for the development of organic production; food safety regulations; sustainable use of pesticides requirements under the plant protection products framework; action plan against antimicrobial resistance; animal health and welfare legislations; legislative and non-legislative initiatives to enhance cooperation of primary producers and improve their competitiveness and position in the food chain; protein strategy; contingency plan for ensuring food supply and food security and communications on food security and fertilizers, the Nature Restoration Regulation, the Zero Pollution Action Plan. R&I will also support the announced Vision for the Fisheries Sector with a 2040 perspective and the European Ocean Pact, a framework of coherence across all policies linked to the ocean. R&I will also be relevant to the outcomes of the evaluation of the common fisheries policy (CFP) and will support its placement under this Pact, as fisheries and aquaculture are affected by other ocean related policies. An important driving force of food systems transformation should be the integration of sectors, actors (including citizens and consumers) and policies. This will involve a better understanding of the multiple interactions between the components of current food systems, to foster solutions that maximise co-benefits with respect to the priorities of Food 2030 [1] . The EU Communication on Boosting Biotechnology and Biomanufacturing in the [2] EU provides an overview of the application of biotechnologies in several sectors including food and feed. R&I activities in this destination will also contribute to achieving the objectives of the Strategy for European Life Sciences, the EU Biotech Act, and the new EU bioeconomy strategy. The Destination supports unlocking the unique assets for research and innovation of the EU outermost regions, in line with the EU strategy for outermost regions [3] . Expected impact : Proposals for topics under this destination should set out credible paths to “ ensuring healthy food and nutrition security by making agriculture, fisheries, aquaculture and food systems sustainable, resilient, inclusive and within planetary boundaries ”. More specifically, proposed topics should contribute to one or more of the following expected impacts : agriculture and food systems contribute to ensuring a secure, safe, sustainable, nutritious, and affordable supply of healthy food in Europe and beyond by fostering its long-term competitiveness, resilience, scalability and sustainability within the boundaries of our planet with the One Health approach; farmers are empowered to ensure the competitiveness, resilience and sustainability of the farming sector, through increasing knowledge, tools, innovative solutions, and advice that allow efficient productivity, working for and with nature, preserving and restoring biodiversity within agricultural ecosystems and helping to decarbonise the EU economy; sustainable fisheries and aquaculture (in marine, brackish and freshwater) contribute to fair, healthy, resilient and environment-friendly food systems in healthy aquatic ecosystems with thriving diversity of species and habitats providing ecosystem and climate services and triggering growth and jobs’ creation in coastal and rural areas; tools are provided so that citizens and communities are empowered to make the sustainable food choices and move towards safe, healthy, nutritious, accessible, affordable and sustainable diets. Insights and advances in life science and digital & data technologies are valorised to deploy solutions in practice across the EU; food businesses, including food processing industries and SMEs, are supported to increase their resilience and competitiveness, while ensuring resource efficiency and sustainability, and human, animal and ecosystem health is preserved. [1] The four priorities of Food2030 are: 1) nutrition and health; 2) climate and environmental sustainability; 3) circularity and resource efficiency; and 4) innovation and empowering communities. [2] https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:52024DC0137. [3] COM(2022) Putting people first, securing sustainable and inclusive growth, unlocking the potential of the EU’s outermost regions.

Hivatkozott dokumentumok

Annex A Horizon Europe Programme Guide Online Manual Standard application form (HE RIA, IA) Standard evaluation form (HE RIA, IA) HE MGA HE Main Work Programme 2026-2027 – 1. General Introduction HE Main Work Programme 2026-2027 – 9. Food, Bioeconomy, Natural Resources, Agriculture and Environment Rules for Legal Entity Validation, LEAR Appointment and Financial Capacity Assessment EU Grants AGA — Annotated Model Grant Agreement Funding & Tenders Portal Terms and Conditions